{
  "contentStorage": "postgres",
  "title": "塞萨尔·米尔斯坦",
  "description": "塞萨尔·米尔斯坦是与克勒共同创立杂交瘤技术的免疫学家，1984年诺贝尔生理学或医学奖得主之一。",
  "url": "/es/people/cesar-milstein.html",
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    "type": "person",
    "title": "塞萨尔·米尔斯坦",
    "slug": "cesar-milstein",
    "aliases": [
      "César Milstein"
    ],
    "summary": "塞萨尔·米尔斯坦是与克勒共同创立杂交瘤技术的免疫学家，1984年诺贝尔生理学或医学奖得主之一。",
    "status": "published",
    "categories": [
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      {
        "id": "s1",
        "title": "César Milstein – Facts",
        "author": "The Nobel Foundation",
        "url": "https://www.nobelprize.org/prizes/medicine/1984/milstein/facts/"
      },
      {
        "id": "s2",
        "title": "The Nobel Prize in Physiology or Medicine 1984",
        "author": "The Nobel Foundation",
        "url": "https://www.nobelprize.org/prizes/medicine/1984/summary/"
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        "id": "s3",
        "title": "塞萨尔·米尔斯坦 – Biographical",
        "author": "The Nobel Foundation",
        "url": "https://www.nobelprize.org/prizes/medicine/1984/milstein/biographical/"
      },
      {
        "id": "s4",
        "title": "塞萨尔·米尔斯坦",
        "author": "Wikipedia",
        "url": "https://zh.wikipedia.org/wiki/%E5%A1%9E%E8%90%A8%E5%B0%94%C2%B7%E7%B1%B3%E5%B0%94%E6%96%AF%E5%9D%A6"
      }
    ],
    "createdAt": "2026-11-01T03:38:01+08:00",
    "updatedAt": "2026-11-02T14:48:32+08:00",
    "updatedBy": "user:admin",
    "revision": 4,
    "body": "**塞萨尔·米尔斯坦**（César Milstein，1927年10月8日—2002年3月24日）出生于布兰卡港（阿根廷），2002年3月24日在剑桥（英国）去世。\n\n## 生平与职业生涯\n\n米尔斯坦在布宜诺斯艾利斯大学获博士学位，后赴剑桥大学分子生物学实验室工作，长期研究抗体结构与多样性。[^s3][^s4]\n\n## 主要成就\n\n米尔斯坦与克勒共同创立杂交瘤技术，使单克隆抗体可大量稳定生产，为疾病诊断、治疗与生物医学研究带来了革命性的工具。[^s3][^s4]\n\n## 获奖\n\n1984 年诺贝尔生理学或医学奖由 3 位得主共享，塞萨尔·米尔斯坦占其中 1/3 份，官方获奖理由（官方原文）：“for theories concerning the specificity in development and control of the immune system and the discovery of the principle for production of monoclonal antibodies”[^s1]。获奖时所属机构为 MRC Laboratory of Molecular Biology，所在地为剑桥（英国）[^s1]。\n\n## 参见\n\n[[work_nobel_prize_1984|1984 年诺贝尔奖]]、[[concept_nobel_prize|诺贝尔奖]]",
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    "birth": {
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      "day": 8,
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      "display": "1927年10月8日"
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    "death": {
      "year": 2002,
      "month": 3,
      "day": 24,
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      "display": "2002年3月24日"
    },
    "occupations": [
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      "slug": "nobel-prize",
      "name": "Premio Nobel",
      "description": "Nobel prizes, their laureates, awarding bodies and yearly lists.",
      "names": {
        "de": "Nobelpreis",
        "en": "Nobel Prize",
        "es": "Premio Nobel",
        "fr": "Prix Nobel",
        "ja": "ノーベル賞",
        "ko": "노벨상",
        "ru": "Нобелевская премия",
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        "zh-hant": "諾貝爾獎"
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      "descriptions": {
        "en": "Nobel prizes, their laureates, awarding bodies and yearly lists.",
        "zh": "诺贝尔奖各奖项、历年名单与相关人物、机构。"
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      "revision": 4,
      "updatedAt": "2026-11-02T14:48:32+08:00",
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      "listId": "work_nobel_prize_1984",
      "listTitle": "1984 年诺贝尔奖",
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      "edition": "1984",
      "name": "塞萨尔·米尔斯坦",
      "tier": "medicine",
      "tierLabel": "诺贝尔生理学或医学奖"
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