{
  "contentStorage": "postgres",
  "title": "戴维·朱利叶斯 · Versioni",
  "description": "戴维·朱利叶斯（David Julius，1955年11月4日—）是2021 年诺贝尔生理学或医学奖得主之一。",
  "url": "/it/people/david-julius/versions.html",
  "entity": {
    "id": "person_nobel_997",
    "type": "person",
    "title": "戴维·朱利叶斯",
    "slug": "david-julius",
    "aliases": [
      "David Julius"
    ],
    "summary": "戴维·朱利叶斯（David Julius，1955年11月4日—）是2021 年诺贝尔生理学或医学奖得主之一。",
    "status": "published",
    "categories": [
      "category-awards",
      "category-people"
    ],
    "tags": [
      "tag-nobel-prize"
    ],
    "sources": [
      {
        "id": "s1",
        "title": "David Julius – Facts",
        "author": "The Nobel Foundation",
        "url": "https://www.nobelprize.org/prizes/medicine/2021/julius/facts/"
      },
      {
        "id": "s2",
        "title": "The Nobel Prize in Physiology or Medicine 2021",
        "author": "The Nobel Foundation",
        "url": "https://www.nobelprize.org/prizes/medicine/2021/summary/"
      },
      {
        "id": "s3",
        "title": "David Julius",
        "author": "Wikipedia",
        "url": "https://en.wikipedia.org/wiki/David_Julius"
      },
      {
        "id": "s4",
        "title": "David Julius – Biographical",
        "author": "The Nobel Foundation",
        "url": "https://www.nobelprize.org/prizes/medicine/2021/julius/biographical/"
      }
    ],
    "createdAt": "2026-11-01T03:38:01+08:00",
    "updatedAt": "2026-11-02T14:59:06+08:00",
    "updatedBy": "user:admin",
    "revision": 5,
    "body": "**戴维·朱利叶斯**（David Julius，1955年11月4日—）出生于纽约（美国）。\n\n## 生平与职业生涯\n\n戴维·朱利叶斯在麻省理工学院获得学士学位，在加州大学伯克利分校师从阿克塞尔获得博士学位，先后在哥伦比亚大学工作，1989年起任教于加州大学旧金山分校。他成长于纽约布鲁克林的海滨社区。[^s4]\n\n## 主要成就\n\n1997年，朱利叶斯团队克隆出辣椒素受体TRPV1：这是感受灼热与辣椒素的离子通道，温度升高或辣椒素结合时开启，让钙离子内流并产生痛觉信号。他随后又鉴定出感受薄荷醇与冷刺激的TRPM8通道，揭示了温度感觉的分子基础，为镇痛药物研发提供了新靶点[^s1]。他还鉴定出感受芥末油等刺激物的TRPA1通道。[^s3]\n\n## 获奖\n\n2021 年诺贝尔生理学或医学奖由 2 位得主共享，戴维·朱利叶斯占其中 1/2 份，官方获奖理由（官方原文）：“for their discoveries of receptors for temperature and touch”[^s1]。获奖时所属机构为 University of California，所在地为旧金山（美国）[^s1]。\n\n## 参见\n\n[[work_nobel_prize_2021|2021 年诺贝尔奖]]、[[concept_nobel_prize|诺贝尔奖]]",
    "url": "/people/david-julius.html",
    "lang": "it",
    "fallback": true,
    "availableLangs": [
      "zh"
    ],
    "birth": {
      "year": 1955,
      "month": 11,
      "day": 4,
      "precision": "day",
      "display": "1955年11月4日"
    }
  },
  "entities": null,
  "versions": [
    {
      "revision": 5,
      "updatedAt": "2026-11-02T14:59:06+08:00",
      "message": "当前版本",
      "hasSnapshot": true,
      "url": "/it/people/david-julius/at/5.html"
    }
  ],
  "lang": "it",
  "availableLangs": [
    "zh"
  ],
  "fallback": true,
  "infoFields": [
    {
      "key": "birth_date",
      "label": "Birth",
      "value": "1955年11月4日"
    }
  ],
  "pagination": {
    "page": 1,
    "pageSize": 50,
    "total": 1,
    "pageCount": 1
  }
}