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  "title": "布莱恩·肯特·科比尔卡 · Relasi",
  "description": "布莱恩·肯特·科比尔卡是解析G蛋白偶联受体结构的生物化学家，2012年诺贝尔化学奖得主之一。",
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    "title": "布莱恩·肯特·科比尔卡",
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    "summary": "布莱恩·肯特·科比尔卡是解析G蛋白偶联受体结构的生物化学家，2012年诺贝尔化学奖得主之一。",
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    "body": "**布莱恩·肯特·科比尔卡**（Brian K. Kobilka，1955年5月30日—）出生于利特尔福尔斯（美国）。\n\n## 生平与职业生涯\n\n科比尔卡在耶鲁大学获医学博士学位，长期任教于斯坦福大学，从事G蛋白偶联受体结构研究。[^s3][^s4]\n\n## 主要成就\n\n科比尔卡解析了β2肾上腺素受体等G蛋白偶联受体的三维结构，揭示其被激活的分子机制，为约三分之一药物的靶点研究提供了结构基础。[^s3][^s4]\n\n## 获奖\n\n2012 年诺贝尔化学奖由 2 位得主共享，布莱恩·肯特·科比尔卡占其中 1/2 份，官方获奖理由（官方原文）：“for studies of G-protein-coupled receptors”[^s1]。获奖时所属机构为 Stanford University School of Medicine，所在地为斯坦福（美国）[^s1]。\n\n## 参见\n\n[[work_nobel_prize_2012|2012 年诺贝尔奖]]、[[concept_nobel_prize|诺贝尔奖]]",
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